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pentobarbital will minimize the level or result of verapamil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.pentobarbital increases toxicity of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. CYP3A4 inducers might enhance the metabolism of ifosfamide to its active alkyl